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Cold outreach with AI that gets replies: the sequence, the deliverability work, and what to measure

Almost every cold outreach guide starts with the copy, and that is the wrong end. Since 1 February 2024 Google has required SPF or DKIM, valid reverse DNS, TLS and a spam rate under 0.3% from every sender to Gmail, with SPF and DKIM together plus DMARC and one-click unsubscribe over 5,000 messages a day. Yahoo added a two-day unsubscribe rule. Microsoft started bouncing unauthenticated high-volume senders with 550 5.7.515. Since November 2025 Google has been ramping enforcement to temporary and permanent rejections. If the mail lands in spam, your best sentence has a reply rate of zero.

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